Introduction to cancer immunotherapy using highly active NK cells

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Characteristics of highly active NK cell therapy

The highly active NK (natural killer) cell therapy using NK cells cultured to increase their “quality and quantity” as much as possible has the following characteristics.

1. For one dosing, as many as about ten to twenty billion activated lymphocytes are administered.

2. The lymphocytes contain a large amount of NK cells and all the lymphocytes other than NK cells are activated T cells (specifically, cytotoxic T cells).

3. Cytotoxicity of NK cells against cancer cells is very high and persists for at least three weeks or so.

4. Various ways to let TRAIL molecule, NKG2D molecule and chemokine receptor function well and to let the production of interferon gamma goes well have been devised so that the NK cells produce strong anticancer effects and enhance the immune function of the whole body.

5. This therapy can enhance the immunity of the whole body early.

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Cancer immunotherapy

Immune system | Cancer immunotherapy | Highly active NK cell therapy | Problems of highly active NK cells | Characteristics of highly active NK cells | “immunity-enhancing effect” of highly active NK cells | Recommendation of highly active NK cell therapy